Calcium-permeable AMPA receptors mediate glutamatergic signaling in neural precursor
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چکیده
2 3 12/25/09 4 5 6 Calcium-permeable AMPA receptors mediate glutamatergic signaling in neural precursor 7 cells of the postnatal olfactory bulb. 8 Authors: Daniel P. Darcy and Jeffry S. Isaacson 9 Affiliation: Department of Neuroscience, University of California, San Diego School of 10 Medicine, La Jolla, California, 92093-0634 11 Running head: Calcium-permeable AMPA receptors in neural precursor cells 12 Correspondence: 13 Jeffry S. Isaacson, PhD 14 Center for Molecular Genetics Rm. 213 15 UCSD Neuroscience, MC 0634 16 9500 Gilman Dr. 17 La Jolla, CA 92093-0634 18 [email protected] 19 20 Articles in PresS. J Neurophysiol (January 20, 2010). doi:10.1152/jn.00821.2009
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Calcium-permeable AMPA receptors mediate glutamatergic signaling in neural precursor cells of the postnatal olfactory bulb.
Neural precursor cells (NPCs) in the mammalian olfactory bulb give rise to local inhibitory neurons that integrate into existing circuitry throughout adult life. However, the functional properties of neurotransmitter receptors expressed by NPCs are not well understood. In this study, we use patch-clamp recording and calcium imaging to explore the properties of glutamate receptors expressed by N...
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